Comparative Effects of Alendronate and Alfacalcidol on Cancellous and Cortical Bone Mass and Bone Mechanical Properties in Ovariectomized Rats
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چکیده
منابع مشابه
Comparative effects of alendronate and alfacalcidol on cancellous and cortical bone mass and bone mechanical properties in ovariectomized rats.
The purpose of the present study was to compare the effects of alendronate and alfacalcidol on cancellous and cortical bone mass and bone mechanical properties in ovariectomized rats. Twenty-six female Sprague-Dawley rats, 7 months of age, were randomized by the stratified weight method into four groups: the sham-operated control (Sham) group and the three ovariectomy (OVX) groups, namely, OVX ...
متن کاملComparative therapeutic effects of alendronate and alfacalcidol on cancellous and cortical bone mass and mechanical properties in ovariectomized osteopenic rats.
The purpose of the present study was to compare the therapeutic effects of alendronate and alfacalcidol on the cancellous and cortical bone mass and mechanical properties in ovariectomized osteopenic rats in a head-to-head fashion. Twenty-five female Sprague-Dawley rats, 7 mo of age, were randomly divided by the stratified weight method into four groups: the sham-operated control (Sham) group a...
متن کاملComparative Therapeutic Effects of Alendronate and AIfacalcidol on Cancellous and Cortical Bone Mass and Mechanical Properties in Ovariectomized Osteopenic Rats
) Departfnefit oj' St)orLs Medjcirte, Kbio Unjversjty School qJ' Medicine, 3 5 Shinanosnachi, Shinjuku-ku, T!)kyo J60-8>-82, Japan ?H[itnri Co,, Ltd,, Tokyo 1IC]-OO05, kipart ]Dcpartment of Neurology, Mitate HospitaL Fukuoka 826-O041, fapan iPeparttnent (ij' Orthvpaedi(' Su ngeru, l,'ujita iealth b'niversity, Ai('hi 47(F 1 J92, Japan i"ietaholistn Laborcttorg, D(rpartrnent qf TVfedjcjrie, IVint...
متن کاملEffects of alendronate and alfacalcidol on the femoral bone mass and bone strength in orchidectomized rats.
The purpose of the present study was to compare the effects of alendronate (ALN) and alfacalcidol (ALF) on the femoral bone mass and bone strength in orchidectomized rats and to clarify the skeletal benefits of combined administration of ALN and ALF. Fifty male Sprague-Dawley rats, 3 months of age, were randomized by the stratified weight method into five groups: the age-matched control (CON), ...
متن کاملEffects of alfacalcidol on cancellous and cortical bone mass in rats treated with glucocorticoid: a bone histomorphometry study.
The beneficial effects of alfacalcidol (ALF) on bone mass, bone formation, and bone resorption have been established in ovariectomized rats. Our previous studies showed that high-dose glucocorticoid (GC) administration (methylprednisolone sodium succinate, 5.0 mg/kg, s.c., 3 times a week) for 4 wk induced cancellous osteopenia without significantly affecting cortical bone mass in Sprague-Dawley...
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ژورنال
عنوان ژورنال: Experimental Animals
سال: 2006
ISSN: 1341-1357,1881-7122
DOI: 10.1538/expanim.55.357